| A new method for noninvasive estimation of ventricular septal defect shunt flow by Doppler color flow mapping: imaging of the laminar flow convergence region on the left septal surface. | |
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MedLine Citation:
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PMID: 1869745 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An accurate but simple and noninvasive method for quantifying flow across a ventricular septal defect has yet to be implemented for routine clinical use. A region of flow convergence is commonly imaged by Doppler color flow mapping on the left septal surface of the ventricular septal defect, appearing as a narrowed region of laminar flow with aliased flow velocities entering the orifice. If the first aliasing region represents a hemispheric isovelocity boundary of a surface of flow convergence and all flow at this surface crosses the ventricular septal defect, the flow through the defect can be estimated by using the radius (R), measured from the first alias to the orifice, and the Nyquist limit (NL) velocity (the flow velocity at the first alias). Doppler color flow imaging was performed in 18 children with a single membranous ventricular septal defect undergoing cardiac catheterization at a mean age of 29.8 months (Group I). Indexes of maximal flow rate across the defect were developed from either the radius or the area, obtained by planimetry, of the first alias, based on Doppler color flow images. All indexes were corrected for body surface area and compared with shunt flow (Qp-Qs) and pulmonary to systemic flow ratio (Qp/Qs) determined at cardiac catheterization. Doppler color flow indexes derived from images of flow convergence in both the long-axis (n = 15) and oblique four-chamber (n = 10) views correlated closely with Qp/Qs (r = 0.71 to 0.92) and Qp - Qs (r = 0.69 to 0.97).(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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V A Moises; B C Maciel; L K Hornberger; A Murillo-Olivas; L M Valdes-Cruz; D J Sahn; R G Weintraub |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of the American College of Cardiology Volume: 18 ISSN: 0735-1097 ISO Abbreviation: J. Am. Coll. Cardiol. Publication Date: 1991 Sep |
Date Detail:
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Created Date: 1991-09-19 Completed Date: 1991-09-19 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8301365 Medline TA: J Am Coll Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 824-32 Citation Subset: AIM; IM |
Affiliation:
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Division of Pediatric Cardiology, University of California, San Diego. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Flow Velocity
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physiology Child, Preschool Coronary Circulation / physiology Echocardiography, Doppler / methods* Female Heart Catheterization Heart Septal Defects, Ventricular / physiopathology, ultrasonography* Heart Septum / ultrasonography Humans Male |
| Grant Support | |
ID/Acronym/Agency:
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R01 HL43287/HL/NHLBI NIH HHS |
| Comments/Corrections | |
Comment In:
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J Am Coll Cardiol. 1991 Sep;18(3):833-6
[PMID:
1869746
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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