Document Detail

A new index for the analysis of heart rate variability dynamics: characterization and application.
MedLine Citation:
PMID:  14658775     Owner:  NLM     Status:  MEDLINE    
A new index for the analysis of the heart rate variability (HRV) dynamics is presented. The proposed index (acceleration change index (ACI)) characterizes the sign of the differences of a time series. A theoretical study shows an expression that relates ACI and the autocorrelation function of the time series. This formula is tested and validated with different simulated time series (uncorrelated noise, sinusoidal and fractional Brownian motion). Next, ACI is applied to RR time series from healthy subjects showing that ACI decreases with periodic controlled breathing, increases during exercise, and it has a lower value at night than during the day. In a preliminary study, ACI has been shown to be lower in healthy subjects than in patients who had suffered a myocardial infarction one month previously. ACI can be employed as a fast and robust new marker of the HRV dynamics.
M A García-González; J Ramos-Castro; M Fernández-Chimeno
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Physiological measurement     Volume:  24     ISSN:  0967-3334     ISO Abbreviation:  Physiol Meas     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-12-08     Completed Date:  2004-07-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9306921     Medline TA:  Physiol Meas     Country:  England    
Other Details:
Languages:  eng     Pagination:  819-32     Citation Subset:  IM    
Instrumentation and Bioengineering Division (DIB), Department of Electronic Engineering (DEE), Universitat Politècnica de Catalunya (UPC), C/Jordi Girona 1-3, Edifici C-4, 08034 Barcelona, Spain.
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MeSH Terms
Circadian Rhythm / physiology
Computer Simulation
Data Interpretation, Statistical
Heart Rate / physiology*
Logistic Models
Myocardial Infarction / physiopathology
ROC Curve

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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