Document Detail

A new fully automatic and robust algorithm for fast segmentation of liver tissue and tumors from CT scans.
MedLine Citation:
PMID:  18369633     Owner:  NLM     Status:  MEDLINE    
Accurate knowledge of the liver structure, including liver surface and lesion localization, is usually required in treatments such as liver tumor ablations and/or radiotherapy. This paper presents a new method and corresponding algorithm for fast segmentation of the liver and its internal lesions from CT scans. No interaction between the user and analysis system is required for initialization since the algorithm is fully automatic. A statistical model-based approach was created to distinguish hepatic tissue from other abdominal organs. It was combined to an active contour technique using gradient vector flow in order to obtain a smoother and more natural liver surface segmentation. Thereafter, automatic classification was performed to isolate hepatic lesions from liver parenchyma. Twenty-one datasets, presenting different anatomical and pathological situations, have been processed and analyzed. Special focus has been driven to the resulting processing time together with quality assessment. Our method allowed robust and efficient liver and lesion segmentations very close to the ground truth, in a relatively short processing time (average of 11.4 s for a 512 x 512-pixel slice). A volume overlap of 94.2% and an accuracy of 3.7 mm were achieved for liver surface segmentation. Sensitivity and specificity for tumor lesion detection were 82.6% and 87.5%, respectively.
Laurent Massoptier; Sergio Casciaro
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-03-28
Journal Detail:
Title:  European radiology     Volume:  18     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-08     Completed Date:  2008-12-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1658-65     Citation Subset:  IM    
Division of Biomedical Engineering Science and Technology, Institute of Clinical Physiology of National Research Council, Campus Ecotekne, via per Monteroni, 73100, Lecce, Italy.
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MeSH Terms
Artificial Intelligence*
Liver / radiography*
Liver Neoplasms / radiography*
Pattern Recognition, Automated / methods*
Radiographic Image Enhancement / methods*
Radiographic Image Interpretation, Computer-Assisted / methods*
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*

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