Document Detail

A new butanolide and a new secobutanolide from Litsea lii var. nunkao-tahangensis.
MedLine Citation:
PMID:  20198535     Owner:  NLM     Status:  MEDLINE    
The chloroform-soluble portion of the leaf extract of Litsea lii var. nunkao-tahangensis was further studied and these studies led to the isolation of a new butanolide, litsealiicolide C (1), and a new secobutanolide, secoisolitsealiicolide B (2), along with seven known compounds, linderanolide B (3), isolinderanolide C (4), secolincomolide A (5), secokotomolide A (6), (+)-beta-eudesmol (7), trans-phytol (8), and (-)-matairesinol (9). Their structures were established on the basis of spectral analysis and comparison with the literature data. In addition, the cytotoxicities against MCF-7, NCI-H460, and SF-268 cancer cell lines were measured in vitro and the results demonstrated that these metabolites have no cytotoxicity against the selected tumour cells.
Ming-Jen Cheng; Tzu-Ann Wang; Shiow-Ju Lee; Ih-Sheng Chen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Natural product research     Volume:  24     ISSN:  1478-6427     ISO Abbreviation:  Nat. Prod. Res.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-19     Completed Date:  2010-07-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101167924     Medline TA:  Nat Prod Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  647-56     Citation Subset:  IM    
Bioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu, ROC.
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MeSH Terms
4-Butyrolactone / chemistry*,  toxicity
Cell Line, Tumor
Cell Proliferation / drug effects
Litsea / chemistry*
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Extracts / chemistry*,  toxicity
Plant Leaves / chemistry*
Reg. No./Substance:
0/Plant Extracts; 96-48-0/4-Butyrolactone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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