Document Detail


A new butanolide and a new secobutanolide from Litsea lii var. nunkao-tahangensis.
MedLine Citation:
PMID:  20198535     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The chloroform-soluble portion of the leaf extract of Litsea lii var. nunkao-tahangensis was further studied and these studies led to the isolation of a new butanolide, litsealiicolide C (1), and a new secobutanolide, secoisolitsealiicolide B (2), along with seven known compounds, linderanolide B (3), isolinderanolide C (4), secolincomolide A (5), secokotomolide A (6), (+)-beta-eudesmol (7), trans-phytol (8), and (-)-matairesinol (9). Their structures were established on the basis of spectral analysis and comparison with the literature data. In addition, the cytotoxicities against MCF-7, NCI-H460, and SF-268 cancer cell lines were measured in vitro and the results demonstrated that these metabolites have no cytotoxicity against the selected tumour cells.
Authors:
Ming-Jen Cheng; Tzu-Ann Wang; Shiow-Ju Lee; Ih-Sheng Chen
Related Documents :
18832035 - Species difference exists in the effects of 1alpha,25(oh)(2)d(3) and its analogue 2-met...
22762035 - Age-related maculopathy susceptibility 2 participates in the phagocytosis functions of ...
15367705 - Differential sensitivity of cancer cells to docosahexaenoic acid-induced cytotoxicity: ...
19428945 - Differential effects of nicotine on retinal and vascular cells in vitro.
25092655 - Edem2 initiates mammalian glycoprotein erad by catalyzing the first mannose trimming step.
22231395 - Plumbagin inhibits cell growth and potentiates apoptosis in human gastric cancer cells ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Natural product research     Volume:  24     ISSN:  1478-6427     ISO Abbreviation:  Nat. Prod. Res.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-19     Completed Date:  2010-07-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101167924     Medline TA:  Nat Prod Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  647-56     Citation Subset:  IM    
Affiliation:
Bioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu, ROC.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
4-Butyrolactone / chemistry*,  toxicity
Cell Line, Tumor
Cell Proliferation / drug effects
Humans
Litsea / chemistry*
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Extracts / chemistry*,  toxicity
Plant Leaves / chemistry*
Chemical
Reg. No./Substance:
0/Plant Extracts; 96-48-0/4-Butyrolactone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Laterality in the rubber hand illusion.
Next Document:  Is desire for social relationships mediated by the serotonergic system in the prefrontal cortex? An ...