| A new boronic acid-based fluorescent sensor for L-dihydroxyphenylalanine. | |
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MedLine Citation:
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PMID: 23229143 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Catecholamines, such as dopamine and L-dihydroxyphenylalanine (L-DOPA), are associated with different physiological functions and diseases. In our recent studies, a novel water-soluble boronic acid compound 3c was identified as a selective fluorescent sensor for L-DOPA. This compound not only has the ability to interact with dopamine and catechol, but also has no fluorescence intensity change for L-DOPA precursors in vivo, such as L-tyrosine. |
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Authors:
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Z Y Wu; X Y Yang; W F Xu; B H Wang; H Fang |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Drug discoveries & therapeutics Volume: 6 ISSN: 1881-7831 ISO Abbreviation: Drug Discov Ther Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-12-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101493809 Medline TA: Drug Discov Ther Country: Japan |
Other Details:
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Languages: eng Pagination: 238-41 Citation Subset: IM |
Affiliation:
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Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmacy, Shandong University, Ji'nan, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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