Document Detail


A new bisphosphonate treatment option for giant cell tumors.
MedLine Citation:
PMID:  11295095     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Treatment of giant cell tumors (GCT) especially in the vertebrae remains controversial. With multidisciplinary treatments, their results are still insufficient. Moreover, GCT shows the potential for malignant transformation and metastasis, additional options such as adjuvant medication must be considered. We report favorable results in three consecutive cases diagnosed with GCT of the spine which were treated with radiotherapy and bisphosphonate (BP) as a new treatment option, and present a review of the literature and a comparison with these case reports.
Authors:
N Fujimoto; K Nakagawa; A Seichi; A Terahara; M Tago; Y Aoki; Y Hosoi; K Ohtomo
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Oncology reports     Volume:  8     ISSN:  1021-335X     ISO Abbreviation:  Oncol. Rep.     Publication Date:    2001 May-Jun
Date Detail:
Created Date:  2001-04-11     Completed Date:  2001-07-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9422756     Medline TA:  Oncol Rep     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  643-7     Citation Subset:  IM    
Affiliation:
Department of Radiation Oncology, University of Tokyo, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Diphosphonates / therapeutic use*
Giant Cell Tumors / pathology,  radiography,  therapy*
Humans
Male
Radiotherapy, Adjuvant
Spinal Neoplasms / pathology,  radiography,  therapy*
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Diphosphonates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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