Document Detail

New automated hepatitis C virus (HCV) core antigen assay as an alternative to real-time PCR for HCV RNA quantification.
MedLine Citation:
PMID:  20351215     Owner:  NLM     Status:  MEDLINE    
An automated hepatitis C virus (HCV) antigen (Ag) assay was evaluated with clinical samples. Determination of HCV Ag and RNA levels in 282 subjects using Abbott HCV Ag and Roche Cobas TaqMan assays revealed that these two tests were highly correlated (r = 0.9464). Thus, the HCV Ag assay could be an alternative test to quantitative reverse transcription-PCR.
Yongjung Park; Jong-Han Lee; Beom Seok Kim; Do Young Kim; Kwang-Hyub Han; Hyon-Suk Kim
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article     Date:  2010-03-29
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  48     ISSN:  1098-660X     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-28     Completed Date:  2010-09-14     Revised Date:  2010-09-28    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2253-6     Citation Subset:  IM    
Department of Laboratory Medicine, Yonsei University College of Medicine, 250 Seongsan-no, Seodaemun-gu, Seoul 120-752, South Korea.
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MeSH Terms
Antigens, Viral / blood*
Automation / methods*
Hepacivirus / isolation & purification*
RNA, Viral / blood
Reverse Transcriptase Polymerase Chain Reaction
Statistics as Topic
Viral Core Proteins / blood*
Viral Load / methods*
Reg. No./Substance:
0/Antigens, Viral; 0/RNA, Viral; 0/Viral Core Proteins; 0/nucleocapsid protein, Hepatitis C virus

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