| A new approach in virtopsy: Postmortem ventilation in multislice computed tomography. | |
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MedLine Citation:
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PMID: 20729123 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although postmortem imaging has gained prominence in the field of forensic medicine, evaluation of the postmortem lung remains problematic. Specifically, differentiation of normal postmortem changes and pathological pulmonary changes is challenging and at times impossible. In this study, five corpses were ventilated using a mechanical ventilator with a pressure of 40 mbar (40.8 cm H(2)O). The ventilation was performed via an endotracheal tube, a larynx mask or a continuous positive airway pressure mask. Postmortem computed tomographic images of the lungs before and with a ventilation of 40 mbar (40.8 cm H(2)O) were evaluated and the lung volumes were measured with segmentation software. Postmortem ventilation led to a clearly visible decrease of both the density in the dependant parts of the lungs and ground glass attenuation, whereas consolidated areas remained unchanged. Furthermore, a mean increase in the lung volume of 2.10 l was seen. Pathological changes such as septal thickening or pulmonary nodules in the lung parenchyma became more detectable with postmortem ventilation. Intracorporal postmortem mechanical ventilation of the lungs appears to be an effective method for enhancing detection of small pathologies of the lung parenchyma as well as for discriminating between consolidation, ground glass attenuation and position-dependent density. |
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Authors:
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Tanja Germerott; Ulrich S Preiss; Lars C Ebert; Thomas D Ruder; Steffen Ross; Patricia M Flach; Garyfalia Ampanozi; Laura Filograna; Michael J Thali |
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Publication Detail:
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Type: Journal Article Date: 2010-08-21 |
Journal Detail:
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Title: Legal medicine (Tokyo, Japan) Volume: 12 ISSN: 1873-4162 ISO Abbreviation: Leg Med (Tokyo) Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-05 Completed Date: 2011-01-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100889186 Medline TA: Leg Med (Tokyo) Country: Ireland |
Other Details:
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Languages: eng Pagination: 276-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Institute of Forensic Medicine, Center of Forensic Imaging and Virtopsy, University of Berne, Berne, Switzerland. tanja.germerott@irm.unibe.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Autopsy / methods* Female Forensic Pathology Humans Imaging, Three-Dimensional / methods Lung / pathology, radiography Male Middle Aged Respiration, Artificial / methods* Tomography, X-Ray Computed / methods* |
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