| A new appraisal of abnormalities of the odontoid process associated with atlanto-axial subluxation and neurological disability. | |
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MedLine Citation:
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PMID: 8149207 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It is well known that abnormalities of the odontoid process may be associated with subluxation and neuraxial compression. Modern computerized imaging is demonstrating that existing classifications are in need of revision since they no longer reflect current views on development, nor do they adequately explain the patterns of abnormality commonly encountered in clinical practice. This study is a description of 62 varied clinical cases examined by high definition computerized myelography or MRI in flexion and extension, some before and after stabilization procedures. From these descriptions, and a review of the old and more recent literature concerning phylogenesis and ontogenesis of the odontoid, the following conclusions were drawn. The dens within the atlas ring is not morphologically a centrum of the first cervical vertebra, but a projection arising from it. In os odontoideum the dens forms normally, but ossifies abnormally because of abnormal motion; it is a result rather than the cause of instability. Hypoplasia of the dens is usually incorrectly diagnosed. When present it is associated with atlanto-occipital assimilation, fusion of the second and third, or more, cervical vertebrae, loss or reduction in axial rotation of the head, basilar invagination and hindbrain deformity of Chiari type. Therefore it is part of a regional anomaly involving hypoplasia of the derivatives of the occipital and upper cervical somites. Recognition of these aspects simplifies both diagnosis and the formulation of therapeutic strategies for different types of clinical presentation. |
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Authors:
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J M Stevens; W K Chong; C Barber; B E Kendall; H A Crockard |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Brain : a journal of neurology Volume: 117 ( Pt 1) ISSN: 0006-8950 ISO Abbreviation: Brain Publication Date: 1994 Feb |
Date Detail:
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Created Date: 1994-05-09 Completed Date: 1994-05-09 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372537 Medline TA: Brain Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 133-48 Citation Subset: AIM; IM |
Affiliation:
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Department of Neuroradiology, National Hospital for Neurology, Maida Vale, London, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Atlanto-Axial Joint / injuries*, physiopathology, radiography Child Dislocations / radiography* Fractures, Bone / radiography Humans Joint Instability / radiography* Odontoid Process / abnormalities*, radiography Tomography, X-Ray Computed |
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