Document Detail


A new amperometric bienzymatic biosensor based on biocomposites for the determination of gluconic acid in wines.
MedLine Citation:
PMID:  21726760     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A new amperometric bienzymatic biosensor for gluconic acid based on the coimmobilization of gluconokinase (EC 2.7.1.12) and phosphogluconate dehydrogenase (EC 1.1.1.44) by polysulfone membrane entrapment onto the surface of a graphite-epoxy composite is reported. This biosensor represents an alternative to gluconate dehydrogenase (EC 1.1.99.3) based methods, which is no longer commercially available. Measurements were done at an applied potential of +0.800V, room temperature and phosphate buffer pH 7.50; obtaining a linear response range for gluconic acid extended from 7.0×10(-6) to 2.5×10(-4)M. Constructed biosensors showed good reproducibility for calibrations using different electrodes (RSD of 1.74%). Finally, biosensor was applied to real wine samples, and the results obtained were validated by comparison with those provided by a reference laboratory. Good correlation was found when the biosensor results were plotted vs. the reference values (slope=1.03±0.04, intercept=0.01±0.02, r(2)=0.995).
Authors:
Xavier Cetó; Francisco Céspedes; Josefina Capdevila; Manel Del Valle
Publication Detail:
Type:  Journal Article     Date:  2011-05-30
Journal Detail:
Title:  Talanta     Volume:  85     ISSN:  1873-3573     ISO Abbreviation:  Talanta     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984816R     Medline TA:  Talanta     Country:  England    
Other Details:
Languages:  eng     Pagination:  1207-12     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier B.V. All rights reserved.
Affiliation:
Sensors and Biosensors Group, Department of Chemistry, Universitat Autònoma de Barcelona, Edifici Cn, 08193 Bellaterra, Barcelona, Spain.
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