| A new Doppler method for quantification of volumetric flow: in vivo validation using color Doppler. | |
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MedLine Citation:
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PMID: 8522693 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: This study was designed to assess the accuracy of a new Doppler method for quantification of volumetric flow in vivo. BACKGROUND: Noninvasive assessment of volumetric flow through heart valves and the great vessels remains a clinical goal. We present a new method for quantification of volumetric flow based on color Doppler mapping that computes velocity vectors over a surface normal to the point of scanning. This Doppler technique assumes only the incompressibility of the fluid. The method is basically independent of the angle of incidence between the ultrasound beam and the direction of blood flow and includes variations of flow area. METHODS: The color Doppler method was tested in seven anesthetized pigs by measuring pulmonary volumetric flows using multiplane Doppler echocardiography. The results were compared with those obtained by the thermodilution technique. In addition, volumetric flows across the mitral valve were determined in 10 normal volunteers by transthoracic Doppler echocardiography and compared with flows obtained with velocity-encoded magnetic resonance imaging (MRI). RESULTS: The mean value of the differences between the thermodilution technique and color Doppler were -0.16 +/- 0.94 liter/min for pulmonary volumetric flows (mean value of differences for [Thermodilution-Color Doppler] +/- 2 SD of differences). The mean value of the differences between MRI and color Doppler were 0.21 +/- 0.83 liter/min for mitral valvular volumetric flows (mean value of differences for [MRI-Color Doppler] +/- 2 SD of differences). CONCLUSIONS: The method showed close agreement with thermodilution and MRI for assessment of volumetric flow in vivo. It is therefore a noninvasive method with potential applications for cardiac output measurement and for quantification of volumetric flow of valvular insufficiency and restrictive lesions. |
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Authors:
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W Y Kim; J K Poulsen; K Terp; N H Staalsen |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the American College of Cardiology Volume: 27 ISSN: 0735-1097 ISO Abbreviation: J. Am. Coll. Cardiol. Publication Date: 1996 Jan |
Date Detail:
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Created Date: 1996-01-25 Completed Date: 1996-01-25 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 8301365 Medline TA: J Am Coll Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 182-92 Citation Subset: AIM; IM |
Affiliation:
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Department of Thoracic and Cardiovascular Surgery, Skejby Sygehus, Aarhus University Hospital, Denmark. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Animals Aorta / physiology, ultrasonography Blood Flow Velocity / physiology Cardiac Output / physiology* Data Interpretation, Statistical Echocardiography, Doppler, Color / methods* Female Humans Magnetic Resonance Imaging Male Mathematical Computing Mitral Valve / pathology, physiology, ultrasonography Pulmonary Artery / pathology, physiology, ultrasonography Reference Values Reproducibility of Results Swine Thermodilution |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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