| A new combination therapy for diabetic gastroparesis | |
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MedLine Citation:
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PMID: 19960400 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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According to our knowledge and for the first time we refer about the combination therapy with gastric electric stimulation and injection of botulinus toxin into the pylorus at a patient with increased symptomatic diabetic gastroparesis for the first time. The prospectively documented gastroparesis-symptom-score improved dramatically under this combination therapy, while time of gastric emptying of 50 % (specified by scintigraphy) was showing solely a low decrease. 18 months after beginning the combination therapy its positive effect is to be watched furthermore, complications haven't occurred yet. The combination therapy with gastric electric stimulation and injection of botulinus toxin into the pylorus demonstrates one option of therapy-refractory diabetic gastroparesis, which has to be verified, however, in prospective studies in terms of its effectiveness. |
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Authors:
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M Hummel; M Fuechtenbusch |
Publication Detail:
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Type: Case Reports; English Abstract; Journal Article Date: 2009-12-03 |
Journal Detail:
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Title: Zeitschrift f?r Gastroenterologie Volume: 47 ISSN: 1439-7803 ISO Abbreviation: Z Gastroenterol Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-12-04 Completed Date: 2010-02-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0033370 Medline TA: Z Gastroenterol Country: Germany |
Other Details:
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Languages: ger Pagination: 1216-20 Citation Subset: IM |
Affiliation:
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Institut f?r Diabetesforschung der Forschergruppe Diabetes e. V. am Helmholtz-Zentrum M?nchen. |
Vernacular Title:
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Neue Kombinationstherapie beidiabetischer Gastroparese. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Botulinum Toxin Type A
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therapeutic use* Combined Modality Therapy / methods Diabetes Mellitus, Type 1 / complications*, therapy* Electric Stimulation Therapy / methods* Gastroparesis / etiology*, therapy* Humans Male Middle Aged Neuromuscular Agents / therapeutic use Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Botulinum Toxin Type A; 0/Neuromuscular Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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