Document Detail


The neuropsychological profile of children at high risk of developing an eating disorder.
MedLine Citation:
PMID:  23021014     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: There is a large body of evidence indicating that eating disorders (EDs) are characterized by particular neuropsychological profiles. We aimed to further explore whether impairments in neuropsychological functioning previously found in ED groups are present prior to onset, or are secondary to the disorder. Method This is the first study to explore neuropsychological functioning in children born to a mother with a lifetime ED, who are therefore at high risk of developing an ED, in a large cohort sample. We investigated intelligence and attention at age 8 years (n = 6201) and working memory (WM) and inhibition at age 10 years (6192) in children who are at high risk of developing an ED, compared to children who are not.
RESULTS: The children of women with lifetime anorexia nervosa (AN) showed high full-scale and performance IQ, increased WM capacity, better visuo-spatial functioning, and decreased attentional control. The children of women with lifetime bulimia nervosa (BN) showed comparatively poor visuo-spatial functioning.
CONCLUSIONS: Our findings suggest that high intelligence, increased WM capacity and impaired attentional control might be intermediate phenotypes on the pathway between genetic vulnerability and the development of an ED.
Authors:
R Kothari; F Solmi; J Treasure; N Micali
Related Documents :
24370344 - Demographic predictors of leukotriene antagonist monotherapy among children with persis...
23024584 - Complementary and alternative medicine use in children and adolescents with type 1 diab...
22036094 - New insights into the natural history of asthma: primary prevention on the horizon.
21741214 - An epidemiological study of children with status epilepticus in okayama, japan: inciden...
18834684 - Changing ictal-onset eeg patterns in children with cortical dysplasia.
18316264 - Association of indoor and outdoor air pollutant level with respiratory problems among c...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-10-01
Journal Detail:
Title:  Psychological medicine     Volume:  43     ISSN:  1469-8978     ISO Abbreviation:  Psychol Med     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-17     Completed Date:  2014-02-17     Revised Date:  2014-03-19    
Medline Journal Info:
Nlm Unique ID:  1254142     Medline TA:  Psychol Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  1543-54     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anorexia Nervosa / genetics,  physiopathology,  psychology*
Attention*
Bulimia Nervosa / genetics,  physiopathology,  psychology*
Child
Child of Impaired Parents / psychology*
Cohort Studies
Executive Function
Female
Genetic Predisposition to Disease
Humans
Inhibition (Psychology)
Intelligence
Male
Memory, Short-Term*
Neuropsychological Tests
Phenotype
Risk Factors
Grant Support
ID/Acronym/Agency:
CS/08/08/14//Department of Health; //Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Whole egg consumption improves lipoprotein profiles and insulin sensitivity to a greater extent than...
Next Document:  A study of Iranian immigrants' experiences of accessing Canadian health care services: a grounded th...