| The neural mechanisms of the effects of transcranial magnetic stimulation on perception. | |
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MedLine Citation:
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PMID: 20457853 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Transcranial magnetic stimulation (TMS) is a technique used to study perceptual, motor, and cognitive functions in the human brain. Its effects have been likened to a "virtual brain lesion," but a direct test of this assumption is lacking. To verify this hypothesis, we measured psychophysically the interaction between the neural activity induced by a visual motion-direction discrimination task and that induced by TMS. The visual stimulus featured two elements: a visual signal (dots that moved coherently in one direction) and visual noise (dots that moved randomly in many directions). Three hypotheses were tested to explain the impairment in performance as a result of TMS: 1) a decrease in signal strength; 2) an induction of randomly distributed neural noise with an accompanying decrement in system sensitivity; and 3) a suppression of relevant information processing and addition of neural noise. We provide evidence in favor of the second hypothesis by showing that TMS basically acts by adding neural noise to the perceptual process. |
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Authors:
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Manuela Ruzzoli; Carlo A Marzi; Carlo Miniussi |
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Publication Detail:
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Type: Journal Article Date: 2010-03-24 |
Journal Detail:
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Title: Journal of neurophysiology Volume: 103 ISSN: 1522-1598 ISO Abbreviation: J. Neurophysiol. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-10 Completed Date: 2010-09-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375404 Medline TA: J Neurophysiol Country: United States |
Other Details:
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Languages: eng Pagination: 2982-9 Citation Subset: IM |
Affiliation:
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Department of Neurological and Vision Sciences, University of Verona, Verona, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analysis of Variance Brain Mapping* Female Humans Logistic Models Male Perception / physiology* Photic Stimulation / methods Reaction Time / physiology Signal Detection, Psychological / physiology* Transcranial Magnetic Stimulation / methods* Visual Cortex / physiology* Young Adult |
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