| The nervous system's potential role in multiple sclerosis associated bone loss. | |
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MedLine Citation:
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PMID: 22579137 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Osteoporosis is a degenerative bone disease that causes significant morbidity and mortality in multiple sclerosis (MS) patients; the pathogenesis of this disease being poorly understood in the context of MS. Osteoporosis is seen more frequently in MS patients than in healthy controls matched for age and sex. Extensively studied factors, including impaired ambulation and the use of steroids, do not appear to completely account for the phenomenon. This review summarizes common risk factors, physiologic and genetic, that may contribute to the etiology and progression of osteoporosis in MS patients as well as providing insight into nervous system control of bone metabolism and homeostasis. |
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Authors:
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Sowmya Josyula; Bijal K Mehta; Yuval Karmon; Barbara Teter; Sonia Batista; Joseph Ostroff; Bianca Weinstock-Guttman |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-10 |
Journal Detail:
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Title: Journal of the neurological sciences Volume: - ISSN: 1878-5883 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Elsevier B.V. All rights reserved. |
Affiliation:
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Dept. of Neurology, SUNY Buffalo, 100 High Street, Buffalo, NY 14203, United States. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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