Document Detail


The neonatal transitional circulation: a combined noninvasive assessment.
MedLine Citation:
PMID:  10149867     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dramatic changes occur in the circulation of the newborn during the transition from fetal to neonatal life. Closure of the foramen ovale and ductus arteriosus, decrease in pulmonary vascular resistance, and improvement in right ventricular compliance are among these changes. These physiological-anatomical events were characterized by means of two-dimensional, Doppler and color flow echocardiography. Forty-five full-term infants (22 male, 23 female) were studied at a mean age of 4.2 hours (T1), 25.5 hours (T2), 49.8 hours (T3), and 73.8 hours (T4) by two-dimensional, Doppler and color flow echocardiography. At T1, T2, T3, and T4, the ductus arteriosus was patent by color flow echocardiography in 100%, 34%, 22%, and 11%, respectively. Conversely, patency of the ductus by Doppler alone was detected in 100% (T1), 13% (T2, T3), and 11% (T4). Reversal of flow in the descending aorta, reflective of diastolic ductal filling, was not sensitive in detecting ductal patency (T1 50%, T2 3%, T3 and T4 0%). The patency of the foramen ovale was noted to decrease over the course of the study. Right ventricular compliance was quantitatively assessed by pulsed-Doppler diastolic properties (E-to-A ratio). This changed significantly from T1 to T4 (0.90 to 0.97) reflecting improving compliance of the right ventricle. The ratio of acceleration to ejection time, a Doppler estimation measure of pulmonary vascular resistance, increased from 0.28 to 0.33 (T1 to T4) reflecting a decrease in pulmonary vascular resistance.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
D S Alenick; I R Holzman; S B Ritter
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  9     ISSN:  0742-2822     ISO Abbreviation:  Echocardiography     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-08-27     Completed Date:  1992-08-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  29-37     Citation Subset:  T    
Affiliation:
Division of Pediatric Cardiology, Mount Sinai Medical Center, New York 10029.
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MeSH Terms
Descriptor/Qualifier:
Blood Circulation / physiology*
Ductus Arteriosus, Patent / physiopathology,  ultrasonography
Echocardiography / methods
Heart Septal Defects, Atrial / physiopathology,  ultrasonography
Humans
Infant, Newborn / physiology*
Pulmonary Artery / physiology,  ultrasonography
Tricuspid Valve Insufficiency / physiopathology,  ultrasonography
Ventricular Function, Right / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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