| The neonatal period: a critical interval in male primate development. | |
| | |
MedLine Citation:
|
PMID: 8708529 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
It appears from the evidence documented in this Commentary that the neonatal period is another critical stage in the process of sexual, behavioural and immune system development and maturation in primates. Interference with normal brain-pituitary-gonadal function during this period (e.g. with a GnRH analogue in monkeys) appears to impact adversely on subsequent reproductive, immunological and behavioural function. These data further emphasize the importance of fully understanding the regulatory mechanisms that govern neonatal gonadal function in the primate, if we are to eliminate, control or minimize the potential risk resulting from its disruption in humans. Given the recent evidence that the reproductive potential of the human male has declined rather dramatically over the last 50 years, and that clinical conditions associated with abnormal testicular function are on the rise, continued investigation in this area would appear to be imperative. |
| | |
Authors:
|
D R Mann; H M Fraser |
Related Documents
:
|
19371369 - Plasticity of ability to form cross-modal representations in infant japanese macaques. 10227739 - Toxicological consequences of feeding pcb congeners to infant rhesus (macaca mulatta) a... 17337159 - Use of barusiban in a novel study design for evaluation of tocolytic agents in pregnant... 23291519 - Neonatal stroke causes poor midline motor behaviors and poor fine and gross motor skill... 19775389 - Gender-specific selection in utero among contemporary human birth cohorts. 10202099 - Infant handling in wild cebus capucinus: testing bonds between females? 2953899 - Nocturnal periodic breathing in adults with down's syndrome. 16699799 - Transfer of reboxetine into breastmilk, its plasma concentrations and lack of adverse e... 8721169 - Extramucosal pyloromyotomy by laparoscopy. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Journal of endocrinology Volume: 149 ISSN: 0022-0795 ISO Abbreviation: J. Endocrinol. Publication Date: 1996 May |
Date Detail:
|
Created Date: 1996-09-12 Completed Date: 1996-09-12 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0375363 Medline TA: J Endocrinol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 191-7 Citation Subset: IM |
Affiliation:
|
Department of Physiology, Morehouse School of Medicine, Atlanta, Georgia 30310-1495, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Animals, Newborn / growth & development, physiology* Brain / drug effects Gonadotropin-Releasing Hormone / agonists, analogs & derivatives Humans Infant, Newborn Male Models, Biological Pituitary Gland / drug effects, growth & development, physiology* Primates / growth & development, physiology* Sexual Maturation / physiology* Testis / drug effects, growth & development, physiology* Testosterone / physiology |
| Chemical | |
Reg. No./Substance:
|
33515-09-2/Gonadotropin-Releasing Hormone; 58-22-0/Testosterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bacillary angiomatosis and mycobacterium infection coexisting in a cutaneous lesion in a patient wit...
Next Document: Expression of IGF-I and IGF-binding protein genes in cirrhotic liver.