Document Detail

The need for ventilatory support during bystander CPR.
MedLine Citation:
PMID:  7661426     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVE: To compare CPR with chest compressions plus ventilatory support (CC+V) and chest compressions alone (CC). DESIGN: Prospective, randomized study. SETTING: Research laboratory. INTERVENTIONS: After 2 minutes of ventricular fibrillation, 18 domestic swine (20 to 35 kg) were treated first with CC or CC+V for 10 minutes, then with standard advanced cardiac life support. RESULTS: Hemodynamics, survival, and neurologic outcome were determined. All 8 swine subjected to CC+V and all 10 subjected to CC showed return of spontaneous circulation. One animal in each group died within 1 hour. Seven of 8 animals in the CC+V group survived for 24 and 48 hours, compared with 9 of 10 CC animals at 24 hours and 8 of 10 at 48 hours. All 48-hour survivors were neurologically normal. CONCLUSION: In this experimental model of bystander CPR, we could not detect a difference in hemodynamics, 48-hour survival, or neurologic outcome when CPR was applied with and without ventilatory support.
R A Berg; D Wilcoxson; R W Hilwig; K B Kern; A B Sanders; C W Otto; D K Eklund; G A Ewy
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of emergency medicine     Volume:  26     ISSN:  0196-0644     ISO Abbreviation:  Ann Emerg Med     Publication Date:  1995 Sep 
Date Detail:
Created Date:  1995-10-04     Completed Date:  1995-10-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8002646     Medline TA:  Ann Emerg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  342-50     Citation Subset:  AIM; IM    
Department of Pediatrics, College of Agriculture, University of Arizona, Tucson, USA.
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MeSH Terms
Cardiopulmonary Resuscitation / methods*
Disease Models, Animal
Emergency Medical Services
Heart Massage / methods*
Oxygen / blood
Random Allocation
Survival Analysis
Time Factors
Treatment Outcome
Ventricular Fibrillation / blood,  physiopathology,  therapy*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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