Document Detail

On the nature of the conditioned stimulus: comment on Leri and Stewart (2002).
MedLine Citation:
PMID:  12498329     Owner:  NLM     Status:  MEDLINE    
F. Leri and J. Stewart (2002) present convincing evidence that a relapse to heroin-seeking behavior is established when rats are given a momentary lapse in which they are allowed to respond while under the influence of heroin. Although exposure to a conditioned stimulus (CS) paired with heroin self-infusion did not induce a relapse, it was able to control responding. In addition to serving as both a discriminative stimulus and a conditioned reinforcer, it is argued in this article that the CS also may have positive hedonic value independent of its association with heroin and that this property should be considered in interpreting the results of future experiments.
Michael T Bardo
Related Documents :
16811659 - Nondiscriminated avoidance of shock by pigeons pecking a key.
16811719 - Stimulus control in a two-choice discrimination procedure.
19560479 - Anxiety-induced cognitive bias in non-human animals.
15062969 - Context preexposure influences the effectiveness of feedback stimuli in avoidance learn...
20354599 - Resistance to change and frequency of response-dependent stimuli uncorrelated with rein...
1167899 - Frequency of reinforcement as a determinant of extinction-induced aggression during err...
19295149 - Phase encoding in the mauthner system: implications in left-right sound source discrimi...
23395309 - Root photomorphogenesis in laboratory-maintained arabidopsis seedlings.
2027519 - Adaptation of the melatonin rhythm in human subjects following night-shift work in anta...
Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Experimental and clinical psychopharmacology     Volume:  10     ISSN:  1064-1297     ISO Abbreviation:  Exp Clin Psychopharmacol     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2002-12-24     Completed Date:  2003-05-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9419066     Medline TA:  Exp Clin Psychopharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  353-5; discussion 364-6     Citation Subset:  IM    
Department of Psychology, University of Kentucky, Lexington 40506-0044, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Conditioning (Psychology) / physiology*
Generalization, Stimulus*
Heroin Dependence / prevention & control
Models, Animal
Comment On:
Exp Clin Psychopharmacol. 2002 Nov;10(4):339-49   [PMID:  12498327 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  How will we know a lapse when we see one? Comment on Leri and Stewart (2002).
Next Document:  Lapses and reinstatement of heroin seeking in rats: comment on Leri and Stewart (2002).