Document Detail

On the nature of the conditioned stimulus: comment on Leri and Stewart (2002).
MedLine Citation:
PMID:  12498329     Owner:  NLM     Status:  MEDLINE    
F. Leri and J. Stewart (2002) present convincing evidence that a relapse to heroin-seeking behavior is established when rats are given a momentary lapse in which they are allowed to respond while under the influence of heroin. Although exposure to a conditioned stimulus (CS) paired with heroin self-infusion did not induce a relapse, it was able to control responding. In addition to serving as both a discriminative stimulus and a conditioned reinforcer, it is argued in this article that the CS also may have positive hedonic value independent of its association with heroin and that this property should be considered in interpreting the results of future experiments.
Michael T Bardo
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Experimental and clinical psychopharmacology     Volume:  10     ISSN:  1064-1297     ISO Abbreviation:  Exp Clin Psychopharmacol     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2002-12-24     Completed Date:  2003-05-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9419066     Medline TA:  Exp Clin Psychopharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  353-5; discussion 364-6     Citation Subset:  IM    
Department of Psychology, University of Kentucky, Lexington 40506-0044, USA.
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MeSH Terms
Conditioning (Psychology) / physiology*
Generalization, Stimulus*
Heroin Dependence / prevention & control
Models, Animal
Comment On:
Exp Clin Psychopharmacol. 2002 Nov;10(4):339-49   [PMID:  12498327 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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