| A naturalistic study of home detoxification from opiates using lofexidine. | |
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MedLine Citation:
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PMID: 9584973 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The study describes the outcome of home detoxification from opiates using lofexidine, a centrally-acting alpha2-adrenergic agonist, in a consecutive series of 28 unselected individuals. Eleven detoxifications (39%) were successful and 17 (61%) unsuccessful. No major medical or psychological problems were reported. Successful outcome was associated with not using heroin, good compliance with a methadone programme and prediction of success by the key worker. Home detoxification using lofexidine appears to be a useful treatment for some opiate-dependent individuals, and is most likely to be successful in those individuals whose drug use is already well-controlled. |
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Authors:
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A S Brown; P M Fleming |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of psychopharmacology (Oxford, England) Volume: 12 ISSN: 0269-8811 ISO Abbreviation: J. Psychopharmacol. (Oxford) Publication Date: 1998 |
Date Detail:
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Created Date: 1998-06-23 Completed Date: 1998-06-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8907828 Medline TA: J Psychopharmacol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 93-6 Citation Subset: IM |
Affiliation:
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Wolston Park Hospital, Queensland, Australia. asb@brain.wph.uq.oz.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Clonidine / analogs & derivatives*, therapeutic use Female Heroin Dependence Humans Male Metabolic Detoxication, Drug Methadone / therapeutic use Narcotic Antagonists / therapeutic use* Narcotics / therapeutic use Opioid-Related Disorders / rehabilitation* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Narcotic Antagonists; 0/Narcotics; 31036-80-3/lofexidine; 4205-90-7/Clonidine; 76-99-3/Methadone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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