Document Detail

The natural history of symptomatic arteriovenous malformations of the brain: a 24-year follow-up assessment.
MedLine Citation:
PMID:  2384776     Owner:  NLM     Status:  MEDLINE    
The authors have updated a series of 166 prospectively followed unoperated symptomatic patients with arteriovenous malformations (AVM's) of the brain. Follow-up data were obtained for 160 (96%) of the original population, with a mean follow-up period of 23.7 years. The rate of major rebleeding was 4.0% per year, and the mortality rate was 1.0% per year. At follow-up review, 23% of the series were dead from AVM hemorrhage. The combined rate of major morbidity and mortality was 2.7% per year. These annual rates remained essentially constant over the entire period of the study. There was no difference in the incidence of rebleeding or death regardless of presentation with or without evidence of hemorrhage. The mean interval between initial presentation and subsequent hemorrhage was 7.7 years.
S L Ondra; H Troupp; E D George; K Schwab
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  73     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-09-18     Completed Date:  1990-09-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  387-91     Citation Subset:  AIM; IM    
Division of Neurosurgery, Walter Reed Army Medical Center, Washington, D.C.
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MeSH Terms
Cerebral Hemorrhage / etiology
Finland / epidemiology
Follow-Up Studies
Intracranial Arteriovenous Malformations* / complications,  mortality
Middle Aged
Seizures / etiology
Survival Rate
Time Factors
Comment In:
J Neurosurg. 1991 Aug;75(2):338-9   [PMID:  2072179 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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