Document Detail

The natural history of single-vessel chronic coronary occlusion: a 25-year experience.
MedLine Citation:
PMID:  9124159     Owner:  NLM     Status:  MEDLINE    
To determine the natural history of patients with a total occlusion of a single coronary artery, we searched the Duke Databank for Cardiovascular Disease to find all patients who underwent a first coronary angiogram >2 days after a symptomatic myocardial infarction between 1969 and 1994. Patients who underwent angiography >30 days after the acute event had a low risk of death in the first year (3%), and a proximal left anterior descending coronary occlusion did not confer substantially higher risk of death (4%). Patients undergoing angiography <30 days after the acute event had a higher mortality (5%), especially those with proximal left anterior descending occlusion (10%). The time from the acute event to angiography was a predictor of death (p = 0.04). Despite low 1-year mortality rates, patients with total occlusion of an isolated coronary vessel treated medically had substantial mortality, myocardial infarction, and revascularization rates over a long-term follow-up period.
J A Puma; M H Sketch; J E Tcheng; L H Gardner; C L Nelson; H R Phillips; R S Stack; R M Califf
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  133     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1997-04-21     Completed Date:  1997-04-21     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  393-9     Citation Subset:  AIM; IM    
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary
Cohort Studies
Coronary Angiography
Coronary Artery Bypass
Coronary Disease / mortality*,  radiography,  therapy
Follow-Up Studies
Heart Catheterization
Middle Aged
Myocardial Infarction / mortality,  radiography,  therapy
Proportional Hazards Models
Risk Factors
Survival Rate
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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