Document Detail

The natural history of late-onset epilepsy secondary to vascular disease.
MedLine Citation:
PMID:  2618579     Owner:  NLM     Status:  MEDLINE    
Twenty-nine patients with late-onset epilepsy were followed prospectively for a mean period of 4.9 years; 14 had CT evidence of occult cerebral infarction and 15 had normal scans. The prognosis was similar in the 2 groups; 57% and 53% respectively became seizure-free. One patient in each group had a myocardial infarction and one patient with occult cerebrovascular disease had a stroke. A separate study was made of the prognosis of 24 patients with epilepsy following stroke (mean follow-up 5.9 years). Twelve of 12 patients with seizure onset within 2 weeks of the stroke became seizure-free, compared with 7/12 with more delayed onset. Late-onset epilepsy has a favourable prognosis, and excellent control should be expected if seizures commence within 2 weeks of stroke.
D R Fish; D H Miller; R C Roberts; J D Blackie; R W Gilliatt
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  80     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-03-08     Completed Date:  1990-03-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  524-6     Citation Subset:  IM    
University Department of Clinical Neurology, National Hospital for Nervous Diseases, London, United Kingdom.
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MeSH Terms
Cerebrovascular Disorders / complications*
Epilepsy / etiology*,  physiopathology
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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