| The natural history of the incidentally discovered small simple pancreatic cyst: long-term follow-up and clinical implications. | |
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MedLine Citation:
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PMID: 15615944 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of our study was to determine the natural history of small (</= 2 cm) simple pancreatic cystic lesions. MATERIALS AND METHODS: A retrospective review was performed of patients with long-term follow-up who were diagnosed with small (</= 2 cm) simple pancreatic cysts on sonography or CT from 1985 to 1996. Long-term surveillance included radiographic surveillance of 5 years or longer, clinical follow-up of 8 years or longer, or response to questionnaire or telephone inquiry 8 year or longer after the original diagnosis. Cause of death was recorded for patients who died within 5-8 years of diagnosis. Patients were excluded if a history of pancreatitis or systemic cystic disease existed. RESULTS: Seventy-nine patients had small simple pancreatic cysts. Forty-nine (62%) had adequate radiologic, clinical, or questionnaire follow-up. Of the 22 patients with radiologic follow-up, 13 (59%) had cysts that remained unchanged or became smaller (mean size, 8 mm; mean follow-up, 9 years), and nine (41%) had cysts that enlarged, from a mean of 14 mm to a mean of 26 mm (mean follow-up, 8 years). Of the 27 patients with clinical or questionnaire follow-up (mean follow-up, 10 years), none developed symptomatic pancreatic disease. Eighteen patients (23%) died within 8 years without adequate radiologic follow-up, none of pancreas-related causes. Twelve patients (15%) were lost to follow-up. CONCLUSION: Although small, incidental, simple pancreatic cysts of 2 cm or smaller may enlarge over a prolonged time, morbidity or mortality due to these small simple cysts is extremely unlikely, and observation appears to be a safe management option. |
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Authors:
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Stephen J Handrich; David M Hough; Joel G Fletcher; Michael G Sarr |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 184 ISSN: 0361-803X ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2004-12-23 Completed Date: 2005-02-25 Revised Date: 2008-02-15 |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 20-3 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, University of Wisconsin Hospital and Clinic, Madison, WI 53792, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Female Follow-Up Studies Humans Male Middle Aged Pancreatic Cyst / diagnosis, pathology* Retrospective Studies |
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