| The natural history of hepatocellular carcinoma. | |
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MedLine Citation:
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PMID: 1315595 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Prospective studies of patients with cirrhosis who are at risk for developing hepatocellular carcinoma (HCC), have greatly improved our understanding of the natural history of this tumour. Despite many studies, the controversy of whether HCC originates from one or more than one clone of transformed liver cells is still unsettled. The natural history of HCC in many instances is an extension of that of the underlying cirrhosis, although the course of the tumour disease may vary from patient to patient and in different geographical areas. In Oriental and southern European patients with HCC, a longer time may elapse between diagnosis and death, than in African blacks. The information about tumour development in non-cirrhotic liver is scanty, due to the little known risk factors for this type of tumour which has impeded performing prospective cohort studies of high risk patients. |
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Authors:
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M Colombo; A Sangiovanni |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: The Italian journal of gastroenterology Volume: 24 ISSN: 0392-0623 ISO Abbreviation: Ital J Gastroenterol Publication Date: 1992 Feb |
Date Detail:
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Created Date: 1992-06-08 Completed Date: 1992-06-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8000544 Medline TA: Ital J Gastroenterol Country: ITALY |
Other Details:
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Languages: eng Pagination: 95-9 Citation Subset: IM |
Affiliation:
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Istituto di Medicina Interna, Università di Milano, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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African Continental Ancestry Group* Asia Asian Continental Ancestry Group* Carcinoma, Hepatocellular / ethnology, etiology*, mortality, pathology Cell Transformation, Neoplastic / pathology* Europe European Continental Ancestry Group* Female Humans Liver / pathology* Liver Cirrhosis / complications*, ethnology, pathology Liver Neoplasms / ethnology, etiology*, mortality, pathology Male Prospective Studies South Africa |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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