Document Detail

The natural history of diabetic nephropathy.
MedLine Citation:
PMID:  2190276     Owner:  NLM     Status:  MEDLINE    
Diabetic nephropathy is now the most common cause of ESRD in the US, and no other complication of diabetes is associated with more deaths. In addition to its impact on morbidity and mortality, it extracts a tremendous cost from the health-care economy. Prevention and better treatment of diabetic renal disease should be a high priority for both the health-care system and society at large. Ultimately, diabetic nephropathy should be preventable, but that goal can be accomplished only by the coordinated efforts between investigators, who work to uncover pathophysiologic processes and design new treatments, and clinicians, who take those findings to the patient's bedside.
K R Tuttle; J H Stein; R A DeFronzo
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in nephrology     Volume:  10     ISSN:  0270-9295     ISO Abbreviation:  Semin. Nephrol.     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-07-11     Completed Date:  1990-07-11     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8110298     Medline TA:  Semin Nephrol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  184-93     Citation Subset:  IM    
Department of Medicine, University of Texas Health Science Center, San Antonio 78284-7882.
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MeSH Terms
Diabetes Mellitus, Type 1 / physiopathology
Diabetes Mellitus, Type 2 / physiopathology
Diabetic Nephropathies / etiology,  physiopathology*
Dietary Proteins / adverse effects
Disease Susceptibility
Hyperglycemia / physiopathology
Hypertension, Renal / physiopathology
Kidney Failure, Chronic / physiopathology
Risk Factors
Reg. No./Substance:
0/Dietary Proteins

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