Document Detail

The natural course of nonsuppurative Calmette-Guérin bacillus lymphadenitis.
MedLine Citation:
PMID:  12150189     Owner:  NLM     Status:  MEDLINE    
In a tertiary level hospital in North India, we studied the outcome of infants with nonsuppurative Calmette-Guérin bacillus (BCG) lymphadenitis managed conservatively. Twenty-three infants with nonsuppurative BCG lymphadenitis diagnosed on the basis of clinical presentation, evidence of granulomatous inflammation and demonstration of acid fast bacilli in the aspirated material were followed prospectively without being offered specific antitubercular drug therapy. Twenty patients were available for final analysis; three were lost to follow-up. Seventeen (85%) had spontaneous regression of BCG lymphadenitis without progression and drainage. The mean time to resolution was 9.1 months. Three (15%) patients developed suppuration and drainage, but even these children had uneventful healing on conservative management only. Nonsuppurative BCG lymphadenitis follows a benign course in most individuals. Most of the cases regress spontaneously with conservative management.
Anupam Singla; Surjit Singh; Jatinder S Goraya; Srinivasan Radhika; Meera Sharma
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  21     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-08-01     Completed Date:  2002-11-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  446-8     Citation Subset:  IM    
Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
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MeSH Terms
BCG Vaccine / adverse effects
Disease Progression
Infant, Newborn
Lymphadenitis / etiology,  microbiology*,  pathology*
Mycobacterium bovis / pathogenicity*
Prospective Studies
Remission, Spontaneous
Reg. No./Substance:
0/BCG Vaccine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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