Document Detail


A nationwide survey of the extent of autopsy in sudden unexplained death in epilepsy.
MedLine Citation:
PMID:  19465799     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sudden unexplained death in epilepsy is a catastrophic event that requires autopsy for definitive diagnosis. Lack of awareness of sudden unexplained death in epilepsy as an important cause of death in epilepsy has been observed among coroners and pathologists. This survey study of US coroners and medical examiners (MEs) assesses their postmortem examinations of persons with epilepsy who had died suddenly without obvious cause. Analysis of the 510 survey responses shows that pathologists are significantly more likely than nonpathologists to inquire routinely about a history of cardiac disease, remove the brain for examination, or collect blood samples for determinations of anticonvulsant and psychotropic drugs. Urban coroners and MEs are significantly more likely than their nonurban colleagues to remove the brain for examination or collect blood samples for these determinations. Lack of family consent and the cost of autopsy are major reasons for not performing an autopsy of persons with epilepsy. Our study underscores the importance of promoting to all coroners and MEs and to the public the need for thorough autopsy of persons with epilepsy when the cause of death is not obvious.
Authors:
Paul L Schraeder; Kristen Delin; Robyn L McClelland; Elson L So
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of forensic medicine and pathology     Volume:  30     ISSN:  1533-404X     ISO Abbreviation:  Am J Forensic Med Pathol     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-05-25     Completed Date:  2009-09-29     Revised Date:  2011-02-02    
Medline Journal Info:
Nlm Unique ID:  8108948     Medline TA:  Am J Forensic Med Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  123-6     Citation Subset:  IM    
Affiliation:
Department of Neurology, Drexel University College of Medicine, Philadelphia, PA, USA.
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MeSH Terms
Descriptor/Qualifier:
Anticonvulsants / blood
Autopsy / economics,  methods,  statistics & numerical data*
Blood Specimen Collection / statistics & numerical data
Coroners and Medical Examiners / statistics & numerical data*
Death, Sudden / etiology*
Epilepsy / complications*
Forensic Pathology
Humans
Physician's Practice Patterns / statistics & numerical data*
Questionnaires
Referral and Consultation / statistics & numerical data
Third-Party Consent
United States
Urban Population
Chemical
Reg. No./Substance:
0/Anticonvulsants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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