Document Detail

The nasal cycle in respiratory defence.
MedLine Citation:
PMID:  11082763     Owner:  NLM     Status:  MEDLINE    
The review describes the phenomenon of the nasal cycle, which consists of periodic congestion and decongestion of the nasal venous sinuses and an alternation of airflow from one side of the nose to the other over a period of several hours. The hypothesis is put forward that the nasal cycle may have a role in respiratory defence by; (a) alternation of the work of air conditioning between the nasal passages (b) generation of a plasma exudate which physically cleanses the epithelium and provides a source of antibodies and inflammatory mediators (c) maintaining the patency of the airway during the inflammatory response to infection.
R B Eccles
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta oto-rhino-laryngologica Belgica     Volume:  54     ISSN:  0001-6497     ISO Abbreviation:  Acta Otorhinolaryngol Belg     Publication Date:  2000  
Date Detail:
Created Date:  2001-03-14     Completed Date:  2001-06-07     Revised Date:  2009-01-14    
Medline Journal Info:
Nlm Unique ID:  0373057     Medline TA:  Acta Otorhinolaryngol Belg     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  281-6     Citation Subset:  IM    
Common Cold and Nasal Research Centre, Cardiff School of Biosciences, Cardiff University, United Kingdom.
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MeSH Terms
Exudates and Transudates / immunology,  secretion
Mucociliary Clearance / physiology
Nasal Cavity / blood supply,  immunology,  physiology*
Paranasal Sinuses / blood supply,  immunology,  physiology*
Respiratory Mucosa / immunology,  physiology
Time Factors

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