| The 'mystery' of opioid-induced diarrhea. | |
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MedLine Citation:
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PMID: 21766071 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Bowel dysfunction, mainly constipation, is a well-known and anticipated side effect of opioids. The physician prescribing an opioid frequently confronts the challenge of preventing and treating bowel dysfunction. Different strategies have emerged for managing opioid-induced constipation. These strategies include physical activity, maintaining adequate fluid intake, adhering to regular daily bowel habits, using laxatives and other anticonstipation medications and, recently, using a peripheral opioid antagonist, either as a separate drug or in the form of an opioid agonistantagonist combination pill. What options exist for the physician when a patient receiving opioids complains of diarrhea, cramps and bloating, rather than the expected constipation? The present article describes a possible cause of opioid-induced diarrhea and strategies for management. |
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Authors:
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Silviu Bril; Yoav Shoham; Jeremy Marcus |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Pain research & management : the journal of the Canadian Pain Society = journal de la société canadienne pour le traitement de la douleur Volume: 16 ISSN: 1203-6765 ISO Abbreviation: Pain Res Manag Publication Date: 2011 May-Jun |
Date Detail:
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Created Date: 2011-07-18 Completed Date: 2011-09-13 Revised Date: 2012-05-01 |
Medline Journal Info:
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Nlm Unique ID: 9612504 Medline TA: Pain Res Manag Country: Canada |
Other Details:
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Languages: eng Pagination: 197-9 Citation Subset: IM |
Affiliation:
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Center for Pain Medicine, Sourasky Medical Center, Tel Aviv, Israel. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Analgesics, Opioid
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adverse effects* Diarrhea / chemically induced*, prevention & control Dose-Response Relationship, Drug Humans Lactose / administration & dosage Morphine / adverse effects* Oxycodone / adverse effects* Pain / drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Opioid; 57-27-2/Morphine; 63-42-3/Lactose; 76-42-6/Oxycodone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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