Document Detail

A mutation in the tomato DDB1 gene affects cell and chloroplast compartment size and CDT1 transcript.
MedLine Citation:
PMID:  19513255     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Fruits harvested from tomato (Solanum lycopersicum) plants carrying mutations at the DAMAGED DNA BINDING PROTEIN 1 gene (SlDDB1; hp-1 and hp-1(w)) are characterized by significantly elevated levels of lycopene and several other phytonutrients. We hypothesize that the pleotropic effect on mutant Slddb1 are some general function of DDB1 protein on cell growth. The main objective of this research was to carry out functional analysis of the mutant SlDDB1 alleles both in-planta and ex-planta in comparison to their normal counterparts. Our major results indicate that: mutant Slddb1 seedlings exhibited delayed growth and smaller cell size, greater chloroplast density, smaller chloroplasts and higher concentration of chlorophyll.Cotyledons cells of Slddb1 mutant also displayed abnormal stomatal pattern, reduced content of CDT1 transcript and altered response to cytokinin. Some of these observations were previously described to be connected to defects in cell cycle control. Our results, coupled with former studies, also suggest that the CDD complex (composed of DDB1, DET1 and COP10) mediate the effect of light and cytokinin activity by possibly regulating the replication licensing factor CDT1 thus affecting both cell size and plastid multiplication.
Nili Caspi; Ilan Levin; Daniel A Chamovitz; Moshe Reuveni
Related Documents :
7828585 - Periodic cdc25c transcription is mediated by a novel cell cycle-regulated repressor ele...
21438635 - Synthesis and biological activity of 22-deoxo-23-oxa analogues of saponin osw-1.
8423235 - An isoform-specific mutation in the protein 4.1 gene results in hereditary elliptocytos...
19170725 - Candidatus desulfovibrio trichonymphae, a novel intracellular symbiont of the flagellat...
9892815 - Metabolic rates of 4-hydroxynonenal in tubular and mesangial cells of the kidney.
22016325 - Cell-cell junctional proteins in cardiovascular mechanotransduction.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Plant signaling & behavior     Volume:  3     ISSN:  1559-2316     ISO Abbreviation:  Plant Signal Behav     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2009-06-10     Completed Date:  2012-10-02     Revised Date:  2013-05-23    
Medline Journal Info:
Nlm Unique ID:  101291431     Medline TA:  Plant Signal Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  641-9     Citation Subset:  -    
Institute of Plant Sciences; The Volcani Center; Bet Dagan, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The electrical response of Phaseolus vulgaris roots to abrupt exposure to hydroquinone.
Next Document:  Just in time for late-LTP: A mechanism for the role of PKMzeta in long-term memory.