| The multiple roles of tissue factor in wound healing. | |
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MedLine Citation:
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PMID: 22202116 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The procoagulant role of tissue factor (TF) is well recognized. The ability to form a hemostatic clot is essential to normal healing of an injury. However, TF also has additional activities as a regulator of cellular processes. Both by production of coagulant molecules that also have cytokine and growth factor-like activities, and by directly mediating cell signaling events, TF has the potential to influence the course and tempo of healing. The literature in this are remains somewhat sparse, but suggests that modulation of TF expression plays a role in modulating the host response to injury. |
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Authors:
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Maureane Hoffman; Dougald M Monroe |
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Publication Detail:
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Type: Journal Article Date: 2012-01-01 |
Journal Detail:
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Title: Frontiers in bioscience (Scholar edition) Volume: 4 ISSN: 1945-0524 ISO Abbreviation: Front Biosci (Schol Ed) Publication Date: 2012 |
Date Detail:
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Created Date: 2011-12-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101485241 Medline TA: Front Biosci (Schol Ed) Country: United States |
Other Details:
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Languages: eng Pagination: 713.-721 Citation Subset: IM |
Affiliation:
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Pathology and Laboratory Medicine Service, Durham VA Medical Center, Durham, NC. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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