| A multifactorial design for studying factors influencing growth and tyramine production of the lactic acid bacteria Lactobacillus brevis CECT 4669 and Enterococcus faecium BIFI-58. | |
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MedLine Citation:
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PMID: 16488576 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A central composite face design was used to study growth and tyramine production of two strains of lactic acid bacteria, Lactobacillus brevis CECT 4669 and Enterococcus faecium BIFI-58. The effects of five physicochemical factors (incubation temperature and time, environmental pH, added tyrosine concentration, and pyridoxal-5-phosphate (PLP) supplementation) on cell growth and tyramine production were analyzed under aerobic and anaerobic conditions. The parameters of the quadratic model for each response variable were estimated by multiple linear regression (MLR), and statistical analysis of the results led to the elucidation of mathematical models capable of predicting the behavior of the responses as a function of the main variables involved in the process. Incubation time was found to be the most important variable influencing growth in L. brevis, while pH showed the highest contribution in E. faecium. The production of tyramine was dependent on the added tyrosine concentration and incubation time. The proposed MLR model predicted the optimum conditions that gave maximum responses for L. brevis and E. faecium growth and tyramine production. In both strains, this model predicted that the anaerobic condition at acidic pH (4.4) in the presence of a high tyrosine concentration favors tyramine production. |
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Authors:
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Angela Marcobal; Pedro Jesús Martín-Alvarez; María Victoria Moreno-Arribas; Rosario Muñoz |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-01-13 |
Journal Detail:
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Title: Research in microbiology Volume: 157 ISSN: 0923-2508 ISO Abbreviation: Res. Microbiol. Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2006-06-06 Completed Date: 2006-08-31 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8907468 Medline TA: Res Microbiol Country: France |
Other Details:
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Languages: eng Pagination: 417-24 Citation Subset: IM |
Affiliation:
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Dpto. Microbiología, Instituto de Fermentaciones Industriales, CSIC, Juan de la Cierva 3, 28006 Madrid, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Culture Media Enterococcus faecium / growth & development, metabolism* Hydrogen-Ion Concentration Lactobacillus brevis / growth & development*, metabolism* Linear Models Pyridoxal Phosphate Temperature Time Factors Tyramine / biosynthesis* Tyrosine |
| Chemical | |
Reg. No./Substance:
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0/Culture Media; 51-67-2/Tyramine; 54-47-7/Pyridoxal Phosphate; 55520-40-6/Tyrosine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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