Document Detail

A multidisciplinary approach to treating maxillofacial arteriovenous malformations in children.
MedLine Citation:
PMID:  19464212     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Congenital arteriovenous malformations (AVMs) in the maxillofacial region are rare, potentially life-threatening, vascular lesions. This study reviewed our experience with a multidisciplinary approach to treating maxillofacial AVMs in children. STUDY DESIGN: Thirteen patients (10 boys and 3 girls) with AVMs involving the facial soft tissues or jaws were treated using a multidisciplinary approach that included: 1) superselective intra-arterial embolization (SIAE); 2) bone wax packing (BWP) of the bone cavity and curettage; and 3) compartmentalization and sclerotherapy. RESULTS: The mean follow-up was 13.5 months, with a range of 6-22 months. The following outcomes were obtained: 9 lesions (69.2%) were completely involuted, 3 lesions (23.1%) were mostly involuted, and 1 lesion (7.7%) was partially involuted. The rates of completely and mostly involuted AVMs involving the jaws treated using SIAE, BWP, and curettage were 80% and 20%, respectively. The rates of completely, mostly, and partially involuted AVMs involving soft tissues treated by compartmentalization and sclerotherapy were 60%, 30%, and 10%, respectively. CONCLUSION: SIAE was reliable for controlling bleeding and as adjunctive treatment for maxillofacial AVMs in children. SIAE followed by BWP of the bone cavity and curettage was a simple, safe, and effective method for treating AVMs of the jaws; SIAE followed by compartmentalization and the injection of OK-432 and pingyangmycin was a reliable alternative treatment for AVMs of the soft tissues in the maxillofacial region.
Wei-liang Chen; Jian-tao Ye; Lin-feng Xu; Zhi-quan Huang; Da-ming Zhang
Publication Detail:
Type:  Journal Article     Date:  2009-05-22
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  108     ISSN:  1528-395X     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-22     Completed Date:  2009-09-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  41-7     Citation Subset:  D; IM    
Department of Oral and Maxillofacial Surgery, Second Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
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MeSH Terms
Arteriovenous Malformations / surgery,  therapy*
Bleomycin / analogs & derivatives,  therapeutic use
Bone Substitutes / therapeutic use
Child, Preschool
Combined Modality Therapy
Drug Combinations
Embolization, Therapeutic / methods
Face / blood supply*
Follow-Up Studies
Hemostatics / therapeutic use
Injections, Intra-Arterial
Mandible / blood supply*
Maxilla / blood supply
Mouth / blood supply
Palmitates / therapeutic use
Picibanil / therapeutic use
Sclerosing Solutions / therapeutic use
Sclerotherapy / methods
Treatment Outcome
Waxes / therapeutic use
Reg. No./Substance:
0/Bone Substitutes; 0/Drug Combinations; 0/Hemostatics; 0/Palmitates; 0/Sclerosing Solutions; 0/Waxes; 11056-06-7/Bleomycin; 11116-32-8/bleomycetin; 39325-01-4/Picibanil; 8021-48-5/bone wax

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