Document Detail


A multicenter reliability study of extremity-magnetic resonance imaging in the longitudinal evaluation of rheumatoid arthritis.
MedLine Citation:
PMID:  17407239     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There are limited data on the reliability of extremity magnetic resonance imaging (E-MRI) in the longitudinal evaluation of rheumatoid arthritis (RA). Our aim was to assess the interreader reliability of the OMERACT RA MRI score in the assessment of change in disease activity and bone erosion scores using 0.2 T E-MRI hand and wrist images from 2 timepoints, evaluated by 3 readers at different international centers. The intraclass correlation coefficients and smallest detectable difference results for the change scores were generally good for erosions and synovitis, but were not acceptable for bone edema. Overall, E-MRI demonstrated ability to detect change comparable to that reported for high-field MRI for erosion and synovitis.
Authors:
Philip G Conaghan; Bo Ejbjerg; Marissa Lassere; Paul Bird; Charles Peterfy; Paul Emery; Fiona McQueen; Espen Haavardsholm; Philip O'Connor; John Edmonds; Harry Genant; Mikkel Østergaard
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Multicenter Study    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  34     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-04     Completed Date:  2007-06-12     Revised Date:  2008-07-24    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  857-8     Citation Subset:  IM    
Affiliation:
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, UK. p.conaghan@leeds.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Adenosine Triphosphatases
Adult
Aged
Arthritis, Rheumatoid / diagnosis,  pathology*
DNA Helicases
Humans
Longitudinal Studies
Magnetic Resonance Imaging / instrumentation,  methods*
Metacarpophalangeal Joint / pathology*
Middle Aged
Observer Variation
Reproducibility of Results
Severity of Illness Index
Synovitis / diagnosis,  pathology*
Wrist Joint / pathology*
Chemical
Reg. No./Substance:
EC 3.6.1.-/Adenosine Triphosphatases; EC 3.6.1.-/DNA Helicases; EC 3.6.1.-/HELB protein, human

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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