| A multicenter, matched case-control study of risk factors for equine laminitis. | |
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MedLine Citation:
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PMID: 11311954 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Risk factors for equine laminitis were examined in a prospective case-control study of the 258 cases seen at six collaborating veterinary teaching hospitals over a 32-month period. Case-control pairs were matched on institution, clinician, and season of diagnosis. The 90% of case-control pairs (78 acute, 155 chronic) that had complete data for age, gender, and breed were used in separate conditional logistic-regression models for acute and chronic laminitis. There was an increase in risk for horses with acute laminitis from 5 to 7 years of age (OR 4.7, 95% CI 1.3-16) and from 13 to 31 years of age (OR 3.9, 95% CI 1.3-12) (both compared to <5 years); risk was increased for chronic laminitis from 10 to 14 years (OR 3, 95% CI 1.4-6.8) and from 15 to 38 years (OR 2.9, 95% CI 1.4-6.1) (both compared to <6 years). Mares - but not stallions - were more likely than geldings to develop acute laminitis (OR 2.6, 95% CI 1.1-6.2) and chronic laminitis (OR 2.0, 95% CI 1.1-3.6). In the small acute-laminitis data set, the breed variable was collapsed into three categories: Thoroughbred (THB, reference), the Quarter Horse (QH), and other (non-QH-THB). The non-QH-THB group was at increased risk of acute laminitis (OR 3.8, 95% CI 1.2-11.8). For the seven breed-group categories used in the chronic-laminitis model, however, all non-THB breed groups appeared significantly at risk as compared to the THB, with odds ratios ranging from 3.3 (95% CI 1.3-8.30) for the QH to 9.1 (95% CI 2.1-39.3) for ponies. |
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Authors:
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P Alford; S Geller; B Richrdson; M Slater; C Honnas; J Foreman; J Robinson; M Messer; M Roberts; D Goble; D Hood; M Chaffin |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Preventive veterinary medicine Volume: 49 ISSN: 0167-5877 ISO Abbreviation: Prev. Vet. Med. Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-04-20 Completed Date: 2001-07-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8217463 Medline TA: Prev Vet Med Country: Netherlands |
Other Details:
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Languages: eng Pagination: 209-22 Citation Subset: IM |
Affiliation:
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Department of Veterinary Anatomy and Public Health, College of Veterinary Medicine, Texas A&M University, Mail Stop 4458, College Station, TX 77843-4458, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Age Factors Animals Breeding Case-Control Studies Chronic Disease Female Foot Diseases / epidemiology, veterinary* Hoof and Claw* Horse Diseases / epidemiology* Horses Incidence Inflammation / epidemiology, veterinary Lameness, Animal / epidemiology* Logistic Models Male Odds Ratio Prospective Studies Risk Factors Sex Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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