| A multicenter comparison study of the Humphrey Field Analyzer I and the Humphrey Field Analyzer II. | |
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MedLine Citation:
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PMID: 9373125 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The purpose of the study is to determine the comparability of the 30-2 full-threshold program in the original Humphrey Field Analyzer (HFA) I to the same test procedure in the new Humphrey Field Analyzer II. METHODS: At each of five clinical centers, one eye of patients with ocular hypertension and normal visual fields, patients with early glaucomatous visual field loss, and patients with more advanced visual field loss were tested with the two instruments plus a retest on a separate HFA I. All participants had undergone at least one prior visual field examination. To minimize the influence of any residual learning or fatigue effects, the order of testing for the three visual field examinations was counterbalanced across subjects. A total of 250 patients were tested (81 patients with ocular hypertension, 81 patients with early glaucomatous visual field loss, and 88 patients with more advanced glaucomatous visual field loss). RESULTS: No statistically significant differences were observed between thresholds, visual field indices, or reliability indices obtained with the HFA I and the HFA II. The small differences between the two instruments were equivalent to the variation observed for test-retest measures using only the HFA I. These results were consistent across the range of visual field characteristics shown by the ocular hypertensive, early glaucoma, and moderate glaucoma patient groups. CONCLUSIONS: The authors' results indicate that there are no differences in the visual field results obtained with the HFA I and the HFA II. These findings suggest that with careful attention to test protocols, the HFA I and HFA II may be used interchangeably to observe patients, even within the context of multicenter clinical trials. |
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Authors:
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C A Johnson; G A Cioffi; S M Drance; D Gaasterland; R P Mills; F Ashburn; P Hnik; R E Van Coevorden |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Ophthalmology Volume: 104 ISSN: 0161-6420 ISO Abbreviation: Ophthalmology Publication Date: 1997 Nov |
Date Detail:
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Created Date: 1997-11-28 Completed Date: 1997-11-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7802443 Medline TA: Ophthalmology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1910-7 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University of California, Davis, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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False Negative Reactions Glaucoma, Open-Angle / physiopathology* Humans Ocular Hypertension / physiopathology* Perimetry / instrumentation, methods* Predictive Value of Tests Reproducibility of Results Sensitivity and Specificity Visual Fields / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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