Document Detail


A multi-scale parameterization approach of peptides for quantitative sequence-activity models.
MedLine Citation:
PMID:  20443765     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A multi-scale parameterization approach, factor analysis scales of generalized amino acid information combined with auto cross covariance, was used to develop quantitative sequence-activity models of peptides using support vector machines. The results demonstrated that this approach could well characterize sequence features of the peptides studied.
Authors:
Weihuan Niu; Qingyou Xia; Guizhao Liang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Protein and peptide letters     Volume:  17     ISSN:  1875-5305     ISO Abbreviation:  Protein Pept. Lett.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-06     Completed Date:  2010-08-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9441434     Medline TA:  Protein Pept Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  591-8     Citation Subset:  IM    
Affiliation:
Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education, Bioengineering college, Chongqing University, Chongqing, China.
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MeSH Terms
Descriptor/Qualifier:
Algorithms
Amino Acid Sequence
Chromatography, Affinity
Computational Biology / methods*
Humans
Imidazoles
Nerve Tissue Proteins / chemistry
Peptides / chemistry*
Physicochemical Phenomena
Protein Interaction Mapping / methods*
Quantitative Structure-Activity Relationship*
Reproducibility of Results
src Homology Domains
Chemical
Reg. No./Substance:
0/Imidazoles; 0/Nerve Tissue Proteins; 0/Peptides; 147954-52-7/amphiphysin; 288-32-4/imidazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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