| Is mucaine an appropriate medication for the relief of heartburn during pregnancy? | |
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MedLine Citation:
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PMID: 2099731 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A double blind comparative study comparing Mucaine, Mucaine without oxethazaine, and placebo was carried out with 50 patients with symptoms of heartburn during late pregnancy. We found that the 2 active treatments were more effective than placebo for the relief of heartburn, but there was no statistically significant difference between groups for the relief of nausea and regurgitation. There was a significant difference in the percentage of days of use of each medication, with the placebo being used least frequently. Although not statistically significant, for the 3 measures for which placebo differed from the active treatments, patients showed a better response to mucaine. This suggests that the addition of oxethazaine may be of benefit. The lack of statistical significance may be due to the relatively small number of cases, and the findings are promising. No side effects were recorded for any treatment. |
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Authors:
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G T Kovacs; J Campbell; D Francis; D Hill; M A Adena |
Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Asia-Oceania journal of obstetrics and gynaecology / AOFOG Volume: 16 ISSN: 0389-2328 ISO Abbreviation: Asia Oceania J Obstet Gynaecol Publication Date: 1990 Dec |
Date Detail:
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Created Date: 1991-08-02 Completed Date: 1991-08-02 Revised Date: 2013-03-25 |
Medline Journal Info:
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Nlm Unique ID: 8102781 Medline TA: Asia Oceania J Obstet Gynaecol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 357-62 Citation Subset: IM |
Affiliation:
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Family Planning Association of Victoria, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aluminum Hydroxide / therapeutic use* Anti-Ulcer Agents / therapeutic use* Double-Blind Method Drug Combinations Ethanolamines / therapeutic use* Female Heartburn / drug therapy* Humans Magnesium Hydroxide / therapeutic use* Pregnancy Pregnancy Complications / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Ulcer Agents; 0/Drug Combinations; 0/Ethanolamines; 1309-42-8/Magnesium Hydroxide; 21645-51-2/Aluminum Hydroxide; 78371-69-4/Oxaine M; IP8QT76V17/oxethazaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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