Document Detail


A mouse homeo box gene, Hox-1.5, and the morphological locus, Hd, map to within 1 cM on chromosome 6.
MedLine Citation:
PMID:  2887485     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mo-10, a homeo box-containing sequence in the Hox-1 complex of genes referred to as Hox-1.5, was found to be polymorphic in inbred and wild mice, and a strain distribution of three allelic forms of Hox-1.5 are reported. The position of Hox-1.5 was mapped in backcross experiments to within 1 cM of the hypodactyly locus on chromosome 6. This identifies the Hd mutation as a useful model for the examination of homeo box expression during mammalian development.
Authors:
B A Mock; L A D'Hoostelaere; R Matthai; K Huppi
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Genetics     Volume:  116     ISSN:  0016-6731     ISO Abbreviation:  Genetics     Publication Date:  1987 Aug 
Date Detail:
Created Date:  1987-10-13     Completed Date:  1987-10-13     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0374636     Medline TA:  Genetics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  607-12     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Chromosome Mapping*
Crosses, Genetic
DNA / isolation & purification
Female
Genes, Homeobox*
Male
Mice
Mice, Inbred Strains / genetics*
Nucleic Acid Hybridization
Recombination, Genetic
Chemical
Reg. No./Substance:
9007-49-2/DNA
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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