Document Detail

The morphology of the lymph node in the macroglobulinaemia of Waldenström.
MedLine Citation:
PMID:  4622624     Owner:  NLM     Status:  MEDLINE    
In 16 cases of Waldenström's macroglobulinaemia the following findings were sufficiently frequent to justify a provisional diagnosis: a modestly enlarged node with lymphocytic infiltration through the capsule into the adjacent connective tissue, retention of the sinus and medullary reticulin pattern, few or no peripheral follicles, sinuses marked out by pale histiocytes, scanty mitoses, numerous plasma cells, and dark staining of plasma in blood vessels. Mast cells were not more frequent than in reactive nodes, but were more frequent than in lymphomas. Periodic acid-Schiff-positive inclusions were found in every case, but were usually very scanty. Similar inclusions can rarely be found in other cases.
C V Harrison
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  25     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1972 Jan 
Date Detail:
Created Date:  1972-06-08     Completed Date:  1972-06-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  12-6     Citation Subset:  AIM; IM    
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MeSH Terms
Adipose Tissue / pathology
Lymph Nodes / pathology*
Lymphoma / pathology
Mast Cells
Middle Aged
Plasma Cells
Waldenstrom Macroglobulinemia / diagnosis,  pathology*

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