Document Detail

The morphology changes in limb leads after ablation of verapamil-sensitive idiopathic left ventricular tachycardia and their correlation with recurrence.
MedLine Citation:
PMID:  18031513     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: This study was designed to explore the morphology changes in limb leads of ECGs after successful ablation of verapamil sensitive idiopathic left ventricular tachycardia (ILVT) and their correlation with tachycardia recurrence. METHODS: Between January 2001 and December 2006, 116 patients who underwent successful ablation of ILVT were included in the study. Twelve-lead surface ECG recordings during sinus rhythm were obtained in all patients before and after ablation to compare morphology changes in limb leads. RESULTS: The ECG morphology changes after ablation were divided into two categories: one with new or deepening Q wave in inferior leads and/or disappearance of Q wave in leads I and aVL, and the other without change. The changes in any Lead II, III, or aVF after ablation occurred significantly more in patients without recurrence of ventricular tachycardia (VT) (P < 0.0001, 0.002, and 0.0001, respectively). The patients with recurrence of VT tended to have no ECG changes, compared with those without recurrence of VT (P = 0.009). The sensitivity of leads II, III, and aVF changes in predicting nonrecurrence VT were 66.7%, 78.7%, and 79.6%, specificity were 100%, 75%, and 87.5%, and nonrecurrence predictive value of 100%, 97.7%, and 98.9%, respectively. When inferior leads changes were combined, they could predict all nonrecurrence patients with 100% specificity. CONCLUSIONS: Successful radiofrequency ablation of ILVT could result in morphology changes in limb leads of ECG, especially in inferior leads. The combined changes in inferior leads can be used as an effective endpoint in ablation of this ILVT.
Shu-Yuan Yao; Jian-Min Chu; Pi-Hua Fang; Kui-Jun Zhang; Jian Ma; Shu Zhang
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2007-11-21
Journal Detail:
Title:  Journal of cardiovascular electrophysiology     Volume:  19     ISSN:  1540-8167     ISO Abbreviation:  J. Cardiovasc. Electrophysiol.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-27     Completed Date:  2008-03-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9010756     Medline TA:  J Cardiovasc Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  238-41     Citation Subset:  IM    
Center of Arrhythmia, Fuwai Cardiovascular Hospital, Peking Union Medical College, Beijing.
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MeSH Terms
Catheter Ablation / methods*
Electrocardiography / methods*
Middle Aged
Recurrence / prevention & control
Statistics as Topic
Tachycardia, Ventricular / complications,  diagnosis*,  surgery*
Treatment Outcome
Vasodilator Agents / diagnostic use
Ventricular Dysfunction, Left / complications,  diagnosis*,  prevention & control*
Verapamil / diagnostic use*
Reg. No./Substance:
0/Vasodilator Agents; 52-53-9/Verapamil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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