| A morphologic study of dermatofibrosarcoma protuberans: expansion of a histologic profile. | |
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MedLine Citation:
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PMID: 10774935 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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RESULTS: The cohort consisted of 42 patients (20 males, 22 females) with a median age at diagnosis of 40 years (range: 10-73 years). Forty-one primary tumors and seven recurrences were evaluated from these 42 patients. Tumor sites included the trunk (22 cases), head and neck (8 cases), upper extremities (7 cases) and lower extremities (6 cases). GCF-like areas were identified in seven (14.6%), multinucleated giant cells in ten (20.8%), hypercellular zones in 12 (25%) and fibrosarcomatous change in six (12.5%) cases, respectively. Combinations included giant cells and GCF-like areas (two cases), giant cells and hypercellular zone (two cases), and GCF-like areas and hypercellular zones (one case). Our findings suggest that DFSP has a wider range of morphologic features, including GCF-like areas, multinucleated giant cells, hypercellular zones and fibrosarcomatous change, than has been previously recognized in the literature. |
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Authors:
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J E Sigel; W F Bergfeld; J R Goldblum |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of cutaneous pathology Volume: 27 ISSN: 0303-6987 ISO Abbreviation: J. Cutan. Pathol. Publication Date: 2000 Apr |
Date Detail:
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Created Date: 2000-05-18 Completed Date: 2000-05-18 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 0425124 Medline TA: J Cutan Pathol Country: DENMARK |
Other Details:
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Languages: eng Pagination: 159-63 Citation Subset: IM |
Affiliation:
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Department of Anatomic Pathology, The Cleveland Clinic Foundation, Ohio, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Child Dermatofibrosarcoma / classification, pathology* Female Fibrosarcoma / pathology Giant Cells / pathology Humans Male Middle Aged Retrospective Studies Skin Neoplasms / classification, pathology* |
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