Document Detail

Is the morphologic mitral valve in discordant atrioventricular connections always normal?
MedLine Citation:
PMID:  18805187     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The purpose of this study was to determine structural features and variations in the mitral valve guarding inflow of the morphologic left ventricle in hearts with discordant atrioventricular connections. METHODS: Morphologic investigation was carried out on the inlet valve to the morphologic left ventricle in 48 autopsied specimens with this particular entity of malformation. RESULTS: The tension apparatus was straddling to the morphologic right ventricle in 2. Another 34 hearts had a bifoliate valve and the papillary muscles abnormally oriented; a solitary papillary muscle in 3, two papillary muscles but deviated in 5, one of two papillary muscles being dysmorphic in 9, and three or more papillary muscles in 17. The origin of these papillary muscles was frequently deviated. In 5 hearts with a trifoliate or quadrifoliate valve, multiple papillary muscles were also the case. One of these had thick leaflets, a part of which was adherent to a membranous flap around the ventricular septal defect as well as to subpulmonary fibrous tissue tags. Eventually, the valve was comparable with the mitral valve seen in the normally structured heart in only 7 hearts (15%). There was no obvious correlation noted between the presence of abnormality in the mitral valve and that in the tricuspid valve. CONCLUSIONS: Architectural abnormalities are not rare in the morphologic mitral valve in this setting. The valvar structure needs precise recognition.
Hideki Uemura; Iki Adachi; Karen P McCarthy; Masahiro Koh; Siew Yen Ho
Related Documents :
7124647 - Digital intravenous ventriculography: analysis and validation of wall thickness changes...
15981857 - Mitral valve function and chordal force distribution using a flexible annulus model: an...
16873937 - A metabolic approach to the treatment of dilated cardiomyopathy in bio t0-2 cardiomyopa...
8132747 - Myocardial protection after whole body heat stress in the rabbit is dependent on metabo...
6715547 - Inhibitors of prostaglandin synthesis or cathepsin b prevent muscle wasting due to seps...
9586787 - The anabolic effects of igf-1 in skeletal muscle after burn injury are not caused by in...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  86     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-22     Completed Date:  2008-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1328-33     Citation Subset:  AIM; IM    
Department of Cardiothoracic Surgery, Royal Brompton Hospital, London, United Kingdom.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Case-Control Studies
Chordae Tendineae / pathology
Double Outlet Right Ventricle / pathology
Heart Defects, Congenital / pathology
Heart Septal Defects, Atrial / pathology*
Heart Septal Defects, Ventricular / pathology*
Mitral Valve / abnormalities*
Pulmonary Atresia / pathology
Reference Values
Retrospective Studies
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Morphologic spectrum of ventriculoarterial connection in hearts with double inlet left ventricle: im...
Next Document:  Management of pulmonary artery sling associated with tracheal stenosis.