| A morphogenetic regulatory role for ethyl alcohol in Candida albicans. | |
| | |
MedLine Citation:
|
PMID: 21605190 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Regulation of morphogenesis through the production of chemical signalling molecules such as isoamyl alcohol, 2-phenylethyl alcohol, 1-dodecanol, E-nerolidol and farnesol is reported in Candida albicans. The present study focuses on the effect of ethyl alcohol on C. albicans dimorphism and biofilm development. Ethyl alcohol inhibited germ tube formation induced by the four standard inducers in a concentration-dependent manner. The germ tube inhibitory concentration (4%) did not have any effect on the growth and viability of C. albicans cells. Ethyl alcohol also inhibited the elongation of germ tubes. Four percentage of ethyl alcohol significantly inhibited biofilm development on polystyrene and silicone surfaces. We suggest a potential morphogenetic regulatory role for ethyl alcohol, which may influence dissemination, virulence and establishment of infection. |
| | |
Authors:
|
Nitin M Chauhan; Jayant S Raut; S Mohan Karuppayil |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-5-23 |
Journal Detail:
|
Title: Mycoses Volume: - ISSN: 1439-0507 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-5-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8805008 Medline TA: Mycoses Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2011 Blackwell Verlag GmbH. |
Affiliation:
|
School of Life Sciences, SRTM University, Nanded, Maharashtra, India. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: In vitro antifungal activity of coumarin extracted from Loeselia mexicana Brand.
Next Document: Endogenous filamentous fungal endophthalmitis - single-centre survey in patients with acute leukaemi...