| The morphogenesis checkpoint: how yeast cells watch their figures. | |
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MedLine Citation:
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PMID: 14644188 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The morphogenesis checkpoint maintains coordination between the process of bud formation and the nuclear events of the cell cycle in yeast. This checkpoint regulates the Wee1 homolog, Swe1p, to induce cell-cycle delay or arrest when aspects of bud formation are defective. A variety of studies have suggested that this checkpoint can monitor actin organization, septin organization, the presence of a bud and even the size of a bud. The evidence for these proposals is reviewed, highlighting recent findings indicating that Swe1p degradation is controlled by the cell shape change that accompanies bud emergence. |
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Authors:
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Daniel J Lew |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Current opinion in cell biology Volume: 15 ISSN: 0955-0674 ISO Abbreviation: Curr. Opin. Cell Biol. Publication Date: 2003 Dec |
Date Detail:
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Created Date: 2003-12-03 Completed Date: 2004-08-09 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 8913428 Medline TA: Curr Opin Cell Biol Country: United States |
Other Details:
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Languages: eng Pagination: 648-53 Citation Subset: IM |
Affiliation:
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Department of Pharmacology and Cancer Biology, Box 3813, Duke University Medical Center, Durham, NC 27710, USA. daniel.lew@duke.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cell Cycle Cell Cycle Proteins Cell Division Genes, Fungal Models, Biological Mutation Protein-Tyrosine Kinases / metabolism Saccharomyces cerevisiae / physiology* Saccharomyces cerevisiae Proteins |
| Chemical | |
Reg. No./Substance:
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0/Cell Cycle Proteins; 0/Saccharomyces cerevisiae Proteins; EC 2.7.1.-/SWE1 protein, S cerevisiae; EC 2.7.10.1/Protein-Tyrosine Kinases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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