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A monkey antigen crossreacting with carcinoembryonic antigen, CEA.
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MedLine Citation:
PMID:  823952     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Normal monkey tissues were found to contain an antigen which crossreacts immunologically with the carcinoembryonic antigen (CEA) of the human digestive tract. The monkey antigen reacted with complete or partial identity to the normal crossreacting antigen (NCA) in humans when tested in immunodiffusion against anti-CEA or anti-NCA. Extracts of monkey tissues inhibited in radioimmunoassays measuring human NCA. It is possible that monkey foetuses and colonic tumours contain CEA.
Authors:
E Engvall; M Vuento; E Ruoslahti
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  British journal of cancer     Volume:  34     ISSN:  0007-0920     ISO Abbreviation:  Br. J. Cancer     Publication Date:  1976 Oct 
Date Detail:
Created Date:  1977-01-03     Completed Date:  1977-01-03     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370635     Medline TA:  Br J Cancer     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  341-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Antigens
Carcinoembryonic Antigen*
Chromatography, Gel
Colonic Neoplasms / immunology
Cross Reactions*
Haplorhini
Humans
Immunodiffusion
Lung / immunology
Macaca / immunology*
Macaca fascicularis / immunology*
Spleen / immunology
Chemical
Reg. No./Substance:
0/Antigens; 0/Carcinoembryonic Antigen
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): Br J Cancer
ISSN: 0007-0920
ISSN: 1532-1827
Article Information
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Print publication date: Month: 10 Year: 1976
Volume: 34 Issue: 4
First Page: 341 Last Page: 345
ID: 2025255
PubMed Id: 823952

A monkey antigen crossreacting with carcinoembryonic antigen, CEA.
E. Engvall
M. Vuento
E. Ruoslahti



Article Categories:
  • Research Article


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