| The monitoring of venous saturations of oxygen in children with congenitally malformed hearts. | |
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MedLine Citation:
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PMID: 19154627 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mixed venous saturation of oxygen has for some time been used as a tool to assess the adequacy of systemic delivery of oxygen in intensive care. In the post-operative child with cardiac disease, it is increasingly being used to assess adequacy of cardiac output. In many of these patients, true sampling of mixed venous saturation of oxygen is not possible due to the infrequent use of pulmonary arterial catheters, or the presence of intra-cardiac left to right shunting leading to mixing of systemic and pulmonary venous blood. The use of saturation of oxygen in the central venous blood as a surrogate for mixed venous saturation of oxygen has been widely investigated in adults, but its use remains controversial. In this review, we discuss the theory behind the use of mixed venous saturation of oxygen in evaluating cardiac output, the problems pertinent to those patients with congenitally malformed hearts, and explore the evidence for central venous saturation of oxygen as a surrogate for mixed venous saturation of oxygen, and its use as a therapeutic target to improve outcomes in this population of patients. |
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Authors:
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Jeff Martin; Lara S Shekerdemian |
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Publication Detail:
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Type: Journal Article; Review Date: 2009-01-20 |
Journal Detail:
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Title: Cardiology in the young Volume: 19 ISSN: 1467-1107 ISO Abbreviation: Cardiol Young Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-09 Completed Date: 2009-06-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9200019 Medline TA: Cardiol Young Country: England |
Other Details:
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Languages: eng Pagination: 34-9 Citation Subset: IM |
Affiliation:
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Department of Paediatric Intensive Care, Birmingham Children's Hospital NHS Trust, Steelhouse Lane, Birmingham, United Kingdom. marttup@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anaerobic Threshold Cardiac Output / physiology Child Child, Preschool Heart Defects, Congenital / physiopathology* Hemodynamics Humans Infant Infant, Newborn Monitoring, Physiologic / methods* Oxygen / blood* Oxygen Consumption / physiology* Oxygen Inhalation Therapy Shock / physiopathology Veins* |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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