Document Detail


The molecular physiology of human limb immobilization and rehabilitation.
MedLine Citation:
PMID:  17031253     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This short review will identify some of the molecular signaling events that regulate atrophy during immobilization in human skeletal muscle and how prescribed exercise rehabilitation may influence these signaling events. The potential for nutritional intervention to positively modulate molecular signaling and thereby offset muscle wasting and/or accelerate rehabilitation in humans will also be considered.
Authors:
Paul L Greenhaff
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Exercise and sport sciences reviews     Volume:  34     ISSN:  0091-6331     ISO Abbreviation:  Exerc Sport Sci Rev     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-10-10     Completed Date:  2007-01-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375434     Medline TA:  Exerc Sport Sci Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  159-63     Citation Subset:  IM    
Affiliation:
Centre for Integrated Systems Biology and Medicine, School of Biomedical Sciences, The Medical School, University of Nottingham, Queen's Medical Centre, Nottingham, United Kingdom. paul.greenaff@nottingham.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Animals
Diet
Gene Expression Profiling
Gene Expression Regulation
Humans
Immobilization*
Muscle, Skeletal / metabolism*
Muscular Atrophy / genetics*,  metabolism,  rehabilitation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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