| A modification for preparing the chronic lung-lymph fistula in sheep. | |
| | |
MedLine Citation:
|
PMID: 7107479 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The sheep lung-lymph model has proven to be a valuable research tool. Preparing this model can be time consuming and may cause considerable trauma to the animal. The standard procedure of Staub et al., the only other published technique, requires three thoracotomies performed on three separate occasions. The objective of this study is to develop and evaluate a less traumatic and time-consuming surgical protocol for preparing the lung-lymph model. This technique enables us to cannulate the efferent lymph duct draining the lung, divide the caudal mediastinal lymph node, and catheterize the left atrium with one thoracotomy. The modified approach, along with some minor changes in aftercare, enables us to have a success rate of over 70% with an average patent flow of 8 days (range 3-21 days) and saves time and surgical trauma to the animal. |
| | |
Authors:
|
M J Brown; D F Erichsen; R Helgerson; J A Will |
Related Documents
:
|
2714819 - Estimating lung mechanics of dogs with unilateral lung injury. 21949729 - A complete solution for dissecting pure main and epistatic effects of qtl in triple tes... 18086689 - Nuclear regulatory authority low energy germanium detection system: performance for the... 8959109 - Exponentially tapered t-tube model in the characterization of arterial non-uniformity. 22198609 - Analysis of combined effects of nonylphenol and monobutyl phthalate on rat sertoli cell... 7007249 - Critique of intermittent mandatory ventilation. 22218319 - Evolutionarily labile species interactions and spatial spread of invasive species. 22139429 - Stable isotope analyses reveal individual variability in the trophic ecology of a top m... 21947129 - Exploring high-d spaces with multiform matrices and small multiples. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
|
Title: Journal of applied physiology: respiratory, environmental and exercise physiology Volume: 52 ISSN: 0161-7567 ISO Abbreviation: J Appl Physiol Publication Date: 1982 Jun |
Date Detail:
|
Created Date: 1982-10-12 Completed Date: 1982-10-12 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7801242 Medline TA: J Appl Physiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1664-6 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Chronic Disease Fistula Lung / physiology*, surgery Lymph Nodes / physiology*, surgery Methods Sheep |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Use of microwave oven for determination of postmortem water volume of lungs.
Next Document: An intercostal retractometer for estimation of intrapleural pressure changes in infants.